California NanoSystems Institute
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Shahrooz Rabizadeh, Ph.D.

Director, Molecular Drug Discovery, Abraxis BioScience
Assistant Adjunct Professor, Bioengineering
Visiting Scholar, California NanoSystems Institute

Ph.D., University of California, Los Angeles, 1994 - 1999
B.S., University of California, Los Angeles, 1988

Contact Information:
Email Address:
Mailing Address: 11755 Wilshire Blvd.
Suite 2000
Los Angeles, CA 90025
Cell-phone Number: (310) 367-5481
Fax Number: (310) 998-8553
Work Phone Number: (310) 983-1046

Selected Publications:

Fombonne Joanna, Rabizadeh Shahrooz, Banwait Surita, Mehlen Patrick, Bredesen Dale E, Selective vulnerability in Alzheimer's disease: amyloid precursor protein and p75(NTR) interaction, Annals of neurology, 2009, 65 (3), 294-303.
Bredesen Dale E, Rabizadeh Shahrooz, APP-based neuroprotective strategies, Current Alzheimer research, 2007, 4 (5), 541-3.
Niazi Kayvan R, Ochoa Maria-Teresa, Sieling Peter A, Rooke Nanette E, Peter Anna K, Mollahan Pamela, Dickey Micah, Rabizadeh Shahrooz, Rea Thomas H, Modlin Robert L, Activation of human CD4+ T cells by targeting MHC class II epitopes to endosomal compartments using human CD1 tail sequences, Immunology, 2007, 122 (4), 522-31.
Ting Adrian, Lichtenthaler Stefan, Xavier Ramnik, Na Soon-Young, Rabizadeh Shahrooz, Holmes Tara, Seed Brian, Large-scale screens for cDNAs with in vivo activity, Novartis Foundation symposium, 2005, 267 (4), 219-29; discussion 229-30.
Castro-Obregón Susana, Rao Rammohan V, del Rio Gabriel, Chen Sylvia F, Poksay Karen S, Rabizadeh Shahrooz, Vesce Sabino, Zhang Xiao-Khun, Swanson Raymond A, Bredesen Dale E, Alternative, nonapoptotic programmed cell death: mediation by arrestin 2, ERK2, and Nur77, The Journal of biological chemistry, 2004, 279 (17), 17543-53.
Bredesen Dale E, Mehlen Patrick, Rabizadeh Shahrooz, Apoptosis and dependence receptors: a molecular basis for cellular addiction, Physiological reviews, 2004, 84 (2), 411-30.
Xavier Ramnik, Rabizadeh Shahrooz, Ishiguro Kazuhiro, Andre Niko, Ortiz J Bernabe, Wachtel Heather, Morris David G, Lopez-Ilasaca Marco, Shaw Albert C, Swat Wojciech, Seed Brian, Discs large (Dlg1) complexes in lymphocyte activation, The Journal of cell biology, 2004, 166 (2), 173-8.
Rabizadeh Shahrooz, Bredesen Dale E, Ten years on: mediation of cell death by the common neurotrophin receptor p75(NTR), Cytokine & growth factor reviews, 2004, 14 (3-4), 225-39.
Rabizadeh Shahrooz, Xavier Ramnik J, Ishiguro Kazuhiro, Bernabeortiz Juliocesar, Lopez-Ilasaca Marco, Khokhlatchev Andrei, Mollahan Pamela, Pfeifer Gerd P, Avruch Joseph, Seed Brian, The scaffold protein CNK1 interacts with the tumor suppressor RASSF1A and augments RASSF1A-induced cell death, The Journal of biological chemistry, 2004, 279 (28), 29247-54.
Juliocesar Bemabe Ortiz, Shahrooz Rabizadeh, Kazuhiro Ishiguro, Marco Lopez-Ilasaca, Andrei Khokhlatchev, Joseph Avruch, Brian Seed, Ramnik Xavier, RASSF1A may serve as novel tumor suppressor gene in gastrointestinal malignancies regulating apoptosis, Gastroenterology, 2003, 124 (4 S1), A288 .
Khokhlatchev Andrei, Rabizadeh Shahrooz, Xavier Ramnik, Nedwidek Maria, Chen Tao, Zhang Xian-feng, Seed Brian, Avruch Joseph, Identification of a novel Ras-regulated proapoptotic pathway, Current biology : CB, 2002, 12 (4), 253-65.