California NanoSystems Institute
CNSI
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Sherven Sharma, Ph.D.

   
Member, California NanoSystems Institute
Professor, Medicine

Education:
Degrees:
Ph.D., University of Southern California, 1993
B.S., University of South Pacific, Fiji Islands, 1979 - 1983

Academic Experience:
Academic Experience:
1993 - 1996 University of California, Los Angeles, Tumor Immunology

Contact Information:
Email Address: ssharma@mednet.ucla.edu
Work Email Address: sharmasp@ucla.edu
Work Email Address: ssharma@mednet.ucla.edu
Mailing Address: UCLA Med-Pul & Critical Care
BOX 951690, 37-131 CHS
Los Angeles, CA 90095
UNITED STATES
Office Address: Main Office
11301 Wilshire Blvd.
Los Angeles, CA 90073
UNITED STATES
Home Page: http://www.lung.med.ucla.edu/home.htm
Home Page: http://www.cancer.ucla.edu/index.aspx?page=243&recordid=550
Fax Number: 310-268-4164 Fax
Work Phone Number: 310-478-3711 Phone
Research Interests:

Medicine - Oncology, Pulmonary Diseases


Technical Research Interest:

Research in Dr. Sherven Sharma's laboratory is geared toward unraveling the mechanisms in the tumor microenvironment that evade host responses and promote and maintain lung tumor growth. Knowledge gained from tumor host interactions is utilized for the development of novel cellular and nanocapsule platform-based immune strategies for lung cancer therapy.



Selected Publications:

Andersson Asa, Yang Seok-Chul, Huang Min, Zhu Li, Kar Upendra K, Batra Raj K, Elashoff David, Strieter Robert M, Dubinett Steven M, Sharma Sherven, IL-7 promotes CXCR3 ligand-dependent T cell antitumor reactivity in lung cancer, Journal of immunology (Baltimore, Md. : 1950), 2009, 182 (11), 6951-8.
Baratelli Felicita, Takedatsu Hiroko, Hazra Saswati, Peebles Katherine, Luo Jie, Kurimoto Pam S, Zeng Gang, Batra Raj K, Sharma Sherven, Dubinett Steven M, Lee Jay M, Pre-clinical characterization of GMP grade CCL21-gene modified dendritic cells for application in a phase I trial in non-small cell lung cancer, Journal of translational medicine, 2008, 6 (3), 38.
Dohadwala Mariam, Yang Seok-Chul, Luo Jie, Sharma Sherven, Batra Raj K, Huang Min, Lin Ying, Goodglick Lee, Krysan Kostyantyn, Fishbein Michael C, Hong Longsheng, Lai Chi, Cameron Robert B, Gemmill Robert M, Drabkin Harry A, Dubinett Steven M, Cyclooxygenase-2-dependent regulation of E-cadherin: prostaglandin E(2) induces transcriptional repressors ZEB1 and snail in non-small cell lung cancer, Cancer research, 2006, 66 (10), 5338-45.
Sharma Sherven, Zhu Li, Yang Seok Chul, Zhang Ling, Lin Jeff, Hillinger Sven, Gardner Brian, Reckamp Karen, Strieter Robert M, Huang Min, Batra Raj K, Dubinett Steven M, Cyclooxygenase 2 inhibition promotes IFN-gamma-dependent enhancement of antitumor responses, Journal of immunology (Baltimore, Md. : 1950), 2005, 175 (2), 813-9.
Sharma Sherven, Yang Seok-Chul, Zhu Li, Reckamp Karen, Gardner Brian, Baratelli Felicita, Huang Min, Batra Raj K, Dubinett Steven M, Tumor cyclooxygenase-2/prostaglandin E2-dependent promotion of FOXP3 expression and CD4+ CD25+ T regulatory cell activities in lung cancer, Cancer research, 2005, 65 (12), 5211-20.
Wang Guanyu, Zhang Jiawei, Liu Luying, Sharma Sherven, Dong Qinghua, Quercetin potentiates doxorubicin mediated antitumor effects against liver cancer through p53/Bcl-xl, PloS one, 2012, 7 (12), e51764.
Srivastava Minu K, Zhu Li, Harris-White Marni, Kar Upendra, Huang Min, Johnson Ming F, Lee Jay M, Elashoff David, Strieter Robert, Dubinett Steven, Sharma Sherven, Myeloid suppressor cell depletion augments antitumor activity in lung cancer, PloS one, 2012, 7 (7), e40677.
Sharma Sherven, Dubinett Steven, Salgia Ravi, CD14(+)S100A9(+) myeloid-derived suppressor cells portend decreased survival in patients with advanced lung cancer, American journal of respiratory and critical care medicine, 2012, 186 (10), 940-1.
Dalwadi Harnisha, Krysan Kostyantyn, Heuze-Vourc'h Nathalie, Dohadwala Mariam, Elashoff David, Sharma Sherven, Cacalano Nicholas, Lichtenstein Alan, Dubinett Steven, Cyclooxygenase-2-dependent activation of signal transducer and activator of transcription 3 by interleukin-6 in non-small cell lung cancer, Clinical cancer research : an official journal of the American Association for Cancer Research, 2005, 11 (21), 7674-82.
Baratelli Felicita, Lin Ying, Zhu Li, Yang Seok-Chul, Heuzé-Vourc'h Nathalie, Zeng Gang, Reckamp Karen, Dohadwala Mariam, Sharma Sherven, Dubinett Steven M, Prostaglandin E2 induces FOXP3 gene expression and T regulatory cell function in human CD4+ T cells, Journal of immunology (Baltimore, Md. : 1950), 2005, 175 (3), 1483-90.
Baratelli Felicita, Krysan Kostyantyn, Heuzé-Vourc'h Nathalie, Zhu Li, Escuadro Brian, Sharma Sherven, Reckamp Karen, Dohadwala Mariam, Dubinett Steven M, PGE2 confers survivin-dependent apoptosis resistance in human monocyte-derived dendritic cells, Journal of leukocyte biology, 2005, 78 (2), 555-64.
Heuzé-Vourc'h Nathalie, Liu Ming, Dalwadi Harnisha, Baratelli Felicita E, Zhu Li, Goodglick Lee, Põld Mehis, Sharma Sherven, Ramirez Ruben D, Shay Jerry W, Minna John D, Strieter Robert M, Dubinett Steven M, IL-20, an anti-angiogenic cytokine that inhibits COX-2 expression, Biochemical and biophysical research communications, 2005, 333 (2), 470-5.
Krysan Kostyantyn, Reckamp Karen L, Dalwadi Harnisha, Sharma Sherven, Rozengurt Enrique, Dohadwala Mariam, Dubinett Steven M, Prostaglandin E2 activates mitogen-activated protein kinase/Erk pathway signaling and cell proliferation in non-small cell lung cancer cells in an epidermal growth factor receptor-independent manner, Cancer research, 2005, 65 (14), 6275-81.
Mao Jenny T, Cui Xiaoyan, Reckamp Karen, Liu Ming, Krysan Kostyantyn, Dalwadi Harnisha, Sharma Sherven, Hazra Saswati, Strieter Robert, Gardner Brian, Dubinett Steven M, Chemoprevention strategies with cyclooxygenase-2 inhibitors for lung cancer, Clinical lung cancer, 2005, 7 (1), 30-9.
Qin Min, Escuadro Brian, Sharma Sherven, Batra Raj K, Gene transfer mediated by native versus fibroblast growth factor-retargeted adenoviral vectors into lung cancer cells, American journal of respiratory cell and molecular biology, 2005, 32 (3), 211-7.
Gamradt Seth C, Feeley Brian T, Liu Nancy Q, Roostaeian Jason, Lin Ying Q, Zhu Li X, Sharma Sherven, Dubinett Steven M, Lieberman Jay R, The effect of cyclooxygenase-2 (COX-2) inhibition on human prostate cancer induced osteoblastic and osteolytic lesions in bone, Anticancer research, 2005, 25 (1A), 107-15.
Strieter Robert M, Belperio John A, Burdick Marie D, Sharma Sherven, Dubinett Steven M, Keane Michael P, CXC chemokines: angiogenesis, immunoangiostasis, and metastases in lung cancer, Annals of the New York Academy of Sciences, 2004, 1028 (1A), 351-60.
Baratelli Felicita E, Heuzé-Vourc'h Nathalie, Krysan Kostyantyn, Dohadwala Mariam, Riedl Karen, Sharma Sherven, Dubinett Steven M, Prostaglandin E2-dependent enhancement of tissue inhibitors of metalloproteinases-1 production limits dendritic cell migration through extracellular matrix, Journal of immunology (Baltimore, Md. : 1950), 2004, 173 (9), 5458-66.
Põld Mehis, Krysan Kostyantyn, Põld Anu, Dohadwala Mariam, Heuze-Vourc'h Nathalie, Mao Jenny T, Riedl Karen L, Sharma Sherven, Dubinett Steven M, Cyclooxygenase-2 modulates the insulin-like growth factor axis in non-small-cell lung cancer, Cancer research, 2004, 64 (18), 6549-55.
Qin Min, Escuadro Brian, Dohadwala Mariam, Sharma Sherven, Batra Raj K, A novel role for the coxsackie adenovirus receptor in mediating tumor formation by lung cancer cells, Cancer research, 2004, 64 (18), 6377-80.
Krysan Kostyantyn, Dalwadi Harnisha, Sharma Sherven, Põld Mehis, Dubinett Steven, Cyclooxygenase 2-dependent expression of survivin is critical for apoptosis resistance in non-small cell lung cancer, Cancer research, 2004, 64 (18), 6359-62.
Zhang Ling, Keane Michael P, Zhu Li X, Sharma Sherven, Rozengurt Enrique, Strieter Robert M, Dubinett Steven M, Huang Min, Interleukin-7 and transforming growth factor-beta play counter-regulatory roles in protein kinase C-delta-dependent control of fibroblast collagen synthesis in pulmonary fibrosis, The Journal of biological chemistry, 2004, 279 (27), 28315-9.
Krysan Kostyantyn, Dohadwala Mariam, Luo Jie, Lin Ying, Zhu Li, Heuze-Vourc'h Nathalie, Goodglick Lee, Merchant Farrukh, Seligson David, Pold Mehis, Strieter Robert, Sharma Sherven, Dubinett Steven, Cyclooxygenase-2-dependent expression of survivin in non-small cell lung cancer, Chest, 2004, 125 (5 Suppl), 140S.
Riedl Karen, Krysan Kostyantyn, Põld Mehis, Dalwadi Harnisha, Heuze-Vourc'h Nathalie, Dohadwala Mariam, Liu Ming, Cui Xiaoyan, Figlin Robert, Mao Jenny T, Strieter Robert, Sharma Sherven, Dubinett Steven M, Multifaceted roles of cyclooxygenase-2 in lung cancer, Drug resistance updates : reviews and commentaries in antimicrobial and anticancer chemotherapy, 2004, 7 (3), 169-84.
Yang Seok-Chul, Hillinger Sven, Riedl Karen, Zhang Ling, Zhu Li, Huang Min, Atianzar Kimberly, Kuo Brian Y, Gardner Brian, Batra Raj K, Strieter Robert M, Dubinett Steven M, Sharma Sherven, Intratumoral administration of dendritic cells overexpressing CCL21 generates systemic antitumor responses and confers tumor immunity, Clinical cancer research : an official journal of the American Association for Cancer Research, 2004, 10 (8), 2891-901.
Põld Mehis, Zhu Li X, Sharma Sherven, Burdick Marie D, Lin Ying, Lee Peter P N, Põld Anu, Luo Jie, Krysan Kostyantyn, Dohadwala Mariam, Mao Jenny T, Batra Raj K, Strieter Robert M, Dubinett Steven M, Cyclooxygenase-2-dependent expression of angiogenic CXC chemokines ENA-78/CXC Ligand (CXCL) 5 and interleukin-8/CXCL8 in human non-small cell lung cancer, Cancer research, 2004, 64 (5), 1853-60.
Gardner Brian, Zhu Li X, Roth Michael D, Tashkin Donald P, Dubinett Steven M, Sharma Sherven, Cocaine modulates cytokine and enhances tumor growth through sigma receptors, Journal of neuroimmunology, 2004, 147 (1-2), 95-8.
Krysan Kostyantyn, Merchant Farrukh H, Zhu Li, Dohadwala Mariam, Luo Jie, Lin Ying, Heuze-Vourc'h Nathalie, Põld Mehis, Seligson David, Chia David, Goodglick Lee, Wang Hejing, Strieter Robert, Sharma Sherven, Dubinett Steven, COX-2-dependent stabilization of survivin in non-small cell lung cancer, FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 2004, 18 (1), 206-8.
Hillinger Sven, Yang Seok-Chul, Zhu Li, Huang Min, Duckett Russell, Atianzar Kimberly, Batra Raj K, Strieter Robert M, Dubinett Steven M, Sharma Sherven, EBV-induced molecule 1 ligand chemokine (ELC/CCL19) promotes IFN-gamma-dependent antitumor responses in a lung cancer model, Journal of immunology (Baltimore, Md. : 1950), 2003, 171 (12), 6457-65.
Riedl Karen, Baratelli Felicita, Batra Raj K, Yang Seok Chul, Luo Jie, Escuadro Brian, Figlin Robert, Strieter Robert, Sharma Sherven, Dubinett Steven, Overexpression of CCL-21/secondary lymphoid tissue chemokine in human dendritic cells augments chemotactic activities for lymphocytes and antigen presenting cells, Molecular cancer, 2003, 2 (12), 35.
Gardner Brian, Zhu Li X, Sharma Sherven, Tashkin Donald P, Dubinett Steven M, Methanandamide increases COX-2 expression and tumor growth in murine lung cancer, FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 2003, 17 (14), 2157-9.
Sharma Sherven, Batra Raj K, Yang Seok Chul, Hillinger Sven, Zhu Li, Atianzar Kimberly, Strieter Robert M, Riedl Karen, Huang Min, Dubinett Steven M, Interleukin-7 gene-modified dendritic cells reduce pulmonary tumor burden in spontaneous murine bronchoalveolar cell carcinoma, Human gene therapy, 2003, 14 (16), 1511-24.
Zhang Ling, Sharma Sherven, Zhu Li X, Kogai Takahiko, Hershman Jerome M, Brent Gregory A, Dubinett Steven M, Huang Min, Nonradioactive iodide effectively induces apoptosis in genetically modified lung cancer cells, Cancer research, 2003, 63 (16), 5065-72.
Qin Min, Chen Shuang, Yu Tina, Escuadro Brian, Sharma Sherven, Batra Raj K, Coxsackievirus adenovirus receptor expression predicts the efficiency of adenoviral gene transfer into non-small cell lung cancer xenografts, Clinical cancer research : an official journal of the American Association for Cancer Research, 2003, 9 (13), 4992-9.
Sharma Sherven, Yang Seok-Chul, Hillinger Sven, Zhu Li X, Huang Min, Batra Raj K, Lin Jeff F, Burdick Marie D, Strieter Robert M, Dubinett Steven M, SLC/CCL21-mediated anti-tumor responses require IFNgamma, MIG/CXCL9 and IP-10/CXCL10, Molecular cancer, 2003, 2 (16), 22.
Zhu Li X, Sharma Sherven, Gardner Brian, Escuadro Brian, Atianzar Kimberly, Tashkin Donald P, Dubinett Steven M, IL-10 mediates sigma 1 receptor-dependent suppression of antitumor immunity, Journal of immunology (Baltimore, Md. : 1950), 2003, 170 (7), 3585-91.
Sharma Sherven, Stolina Marina, Yang Seok-Chul, Baratelli Felicita, Lin Jeff F, Atianzar Kimberly, Luo Jie, Zhu Li, Lin Ying, Huang Min, Dohadwala Mariam, Batra Raj K, Dubinett Steven M, Tumor cyclooxygenase 2-dependent suppression of dendritic cell function, Clinical cancer research : an official journal of the American Association for Cancer Research, 2003, 9 (3), 961-8.
Heuze-Vourc'h Nathalie, Zhu Li, Krysan Kostyantyn, Batra Raj K, Sharma Sherven, Dubinett Steven M, Abnormal interleukin 10Ralpha expression contributes to the maintenance of elevated cyclooxygenase-2 in non-small cell lung cancer cells, Cancer research, 2003, 63 (4), 766-70.
Batra Raj K, Lin Ying, Sharma Sherven, Dohadwala Mariam, Luo Jie, Pold Mehis, Dubinett Steven M, Non-small cell lung cancer-derived soluble mediators enhance apoptosis in activated T lymphocytes through an I kappa B kinase-dependent mechanism, Cancer research, 2003, 63 (3), 642-6.
Sharma Sherven, Huang Min, Dohadwala Mariam, Pold Mehis, Batra Raj K, Dubinett Steven M, Cyclooxygenase 2-dependent regulation of antitumor immunity in lung cancer, Methods in molecular medicine, 2003, 75 (3), 723-36.
Sharma Sherven, Yang Seok Chul, Batra Raj K, Dubinett Steven M, Intratumoral therapy with cytokine gene-modified dendritic cells in murine lung cancer models, Methods in molecular medicine, 2003, 75 (3), 711-22.
Batra Raj K, Bernal Raymond M, Sharma Sherven, Identifying obstacles to viral gene therapy for lung cancer. Malignant pleural effusions as a paradigm, Methods in molecular medicine, 2003, 75 (3), 545-59.
Dohadwala Mariam, Batra Raj K, Luo Jie, Lin Ying, Krysan Kostyantyn, Pold Mehis, Sharma Sherven, Dubinett Steven M, Autocrine/paracrine prostaglandin E2 production by non-small cell lung cancer cells regulates matrix metalloproteinase-2 and CD44 in cyclooxygenase-2-dependent invasion, The Journal of biological chemistry, 2002, 277 (52), 50828-33.
Dubinett Steven M, Sharma Sherven, Huang Min, Dohadwala Mariam, Pold Mehis, Mao Jenny T, Cyclooxygenase-2 in lung cancer, Progress in experimental tumor research, 2003, 37 (3), 138-62.
Bernal Ray M, Sharma Sherven, Gardner Brian K, Douglas Joanne T, Bergelson Jeffrey M, Dubinett Steven M, Batra Raj K, Soluble coxsackievirus adenovirus receptor is a putative inhibitor of adenoviral gene transfer in the tumor milieu, Clinical cancer research : an official journal of the American Association for Cancer Research, 2002, 8 (6), 1915-23.
Basak Saroj K, Harui Airi, Stolina Marina, Sharma Sherven, Mitani Kohnosuke, Dubinett Steven M, Roth Michael D, Increased dendritic cell number and function following continuous in vivo infusion of granulocyte macrophage-colony-stimulating factor and interleukin-4, Blood, 2002, 99 (8), 2869-79.
Huang Min, Sharma Sherven, Zhu Li X, Keane Michael P, Luo Jie, Zhang Ling, Burdick Marie D, Lin Ying Q, Dohadwala Mariam, Gardner Brian, Batra Raj K, Strieter Robert M, Dubinett Steven M, IL-7 inhibits fibroblast TGF-beta production and signaling in pulmonary fibrosis, The Journal of clinical investigation, 2002, 109 (7), 931-7.
Gardner Brian, Zu Li X, Sharma Sherven, Liu Qian, Makriyannis Alexandros, Tashkin Donald P, Dubinett Steven M, Autocrine and paracrine regulation of lymphocyte CB2 receptor expression by TGF-beta, Biochemical and biophysical research communications, 2002, 290 (1), 91-6.
Sharma Sherven, Srivastava Minu K, Harris-White Marni, Lee Jay Moon, Dubinett Steven, MUC1 peptide vaccine mediated antitumor activity in non-small cell lung cancer, Expert opinion on biological therapy, 2011, 11 (8), 987-90.
Andersson Asa, Srivastava Minu K, Harris-White Marni, Huang Min, Zhu Li, Elashoff David, Strieter Robert M, Dubinett Steven M, Sharma Sherven, Role of CXCR3 ligands in IL-7/IL-7R alpha-Fc-mediated antitumor activity in lung cancer, Clinical cancer research : an official journal of the American Association for Cancer Research, 2011, 17 (11), 3660-72.
Kar Upendra K, Srivastava Minu K, Andersson Asa, Baratelli Felicita, Huang Min, Kickhoefer Valerie A, Dubinett Steven M, Rome Leonard H, Sharma Sherven, Novel CCL21-vault nanocapsule intratumoral delivery inhibits lung cancer growth, PloS one, 2011, 6 (5), e18758.
Herrmann Ines, Baeuerle Patrick A, Friedrich Matthias, Murr Alexander, Filusch Susanne, Rüttinger Dominik, Majdoub Mariam W, Sharma Sherven, Kufer Peter, Raum Tobias, Münz Markus, Highly efficient elimination of colorectal tumor-initiating cells by an EpCAM/CD3-bispecific antibody engaging human T cells, PloS one, 2010, 5 (10), e13474.
Dubinett Steven M, Lee Jay M, Sharma Sherven, Mulé James J, Chemokines: can effector cells be redirected to the site of the tumor?, Cancer journal (Sudbury, Mass.), 2010, 16 (4), 325-35.
Baratelli Felicita, Lee Jay M, Hazra Saswati, Lin Ying, Walser Tonya C, Schaue Dorthe, Pak Peter S, Elashoff David, Reckamp Karen, Zhang Ling, Fishbein Michael C, Sharma Sherven, Dubinett Steven M, PGE(2) contributes to TGF-beta induced T regulatory cell function in human non-small cell lung cancer, American journal of translational research, 2010, 2 (4), 356-67.
Yanagawa Jane, Walser Tonya C, Zhu Li X, Hong Longsheng, Fishbein Michael C, Mah Vei, Chia David, Goodglick Lee, Elashoff David A, Luo Jie, Magyar Clara E, Dohadwala Mariam, Lee Jay M, St John Maie A, Strieter Robert M, Sharma Sherven, Dubinett Steven M, Snail promotes CXCR2 ligand-dependent tumor progression in non-small cell lung carcinoma, Clinical cancer research : an official journal of the American Association for Cancer Research, 2009, 15 (22), 6820-9.
St John Maie A, Dohadwala Mariam, Luo Jie, Wang Guanyu, Lee Gina, Shih Hubert, Heinrich Eileen, Krysan Kostantyn, Walser Tonya, Hazra Saswati, Zhu Li, Lai Chi, Abemayor Elliot, Fishbein Michael, Elashoff David A, Sharma Sherven, Dubinett Steven M, Proinflammatory mediators upregulate snail in head and neck squamous cell carcinoma, Clinical cancer research : an official journal of the American Association for Cancer Research, 2009, 15 (19), 6018-27.
Sharma Sherven, Zhu Li, Davoodi Michael, Harris-White Marni, Lee Jay M, St John Maie, Salgia Ravi, Dubinett Steven, TLR3 agonists and proinflammatory antitumor activities, Expert opinion on therapeutic targets, 2013, 17 (5), 481-3.
Dubinett Steven, Sharma Sherven, Towards effective immunotherapy for lung cancer: simultaneous targeting of tumor-initiating cells and immune pathways in the tumor microenvironment, Immunotherapy, 2009, 1 (5), 721-5.
Srivastava Minu K, Dubinett Steven, Sharma Sherven, Targeting MDSCs enhance therapeutic vaccination responses against lung cancer, Oncoimmunology, 2012, 1 (9), 1650-1651.
Veena Mysore S, Qin Min, Andersson Asa, Sharma Sherven, Batra Raj K, CAR mediates efficient tumor engraftment of mesenchymal type lung cancer cells, Laboratory investigation; a journal of technical methods and pathology, 2009, 89 (8), 875-86.
Basak Saroj K, Veena Mysore S, Oh Scott, Huang Ge, Srivatsan Eri, Huang Min, Sharma Sherven, Batra Raj K, The malignant pleural effusion as a model to investigate intratumoral heterogeneity in lung cancer, PloS one, 2009, 4 (6), e5884.
Dennis Miranda, Wang Guanyu, Luo Jie, Lin Yuan, Dohadwala Mariam, Abemayor Elliot, Elashoff David A, Sharma Sherven, Dubinett Steven M, St John Maie A, Snail controls the mesenchymal phenotype and drives erlotinib resistance in oral epithelial and head and neck squamous cell carcinoma cells, Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery, 2012, 147 (4), 726-32.
Sharma Sherven, Andersson Asa, Adenovirus E3 proteins help tumors to evade innate and adaptive immune responses, Cancer biology & therapy, 2009, 8 (12), 1133-5.
Walser Tonya, Cui Xiaoyan, Yanagawa Jane, Lee Jay M, Heinrich Eileen, Lee Gina, Sharma Sherven, Dubinett Steven M, Smoking and lung cancer: the role of inflammation, Proceedings of the American Thoracic Society, 2008, 5 (8), 811-5.
Lee Jay M, Yanagawa Jane, Peebles Katherine A, Sharma Sherven, Mao Jenny T, Dubinett Steven M, Inflammation in lung carcinogenesis: new targets for lung cancer chemoprevention and treatment, Critical reviews in oncology/hematology, 2008, 66 (3), 208-17.
Hu David, Lau Ontario D, Wang Linda, Wang Guanyu, Schaue Dorthe, Zhu Li, Huang Min, Lin Yuan, Dennis Miranda, Abemayor Elliot, Elashoff David A, Dubinett Steven M, McBride William H, Sharma Sherven, Wu Ben, St John Maie A, A novel modular polymer platform for the treatment of head and neck squamous cell carcinoma in an animal model, Archives of otolaryngology--head & neck surgery, 2012, 138 (4), 412-7.
Reckamp Karen L, Gardner Brian K, Figlin Robert A, Elashoff David, Krysan Kostyantyn, Dohadwala Mariam, Mao Jenny, Sharma Sherven, Inge Landon, Rajasekaran Ayyappan, Dubinett Steven M, Tumor response to combination celecoxib and erlotinib therapy in non-small cell lung cancer is associated with a low baseline matrix metalloproteinase-9 and a decline in serum-soluble E-cadherin, Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer, 2008, 3 (2), 117-24.
Srivastava Minu K, Andersson Åsa, Zhu Li, Harris-White Marni, Lee Jay M, Dubinett Steven, Sharma Sherven, Myeloid suppressor cells and immune modulation in lung cancer, Immunotherapy, 2012, 4 (3), 291-304.
Krysan Kostyantyn, Lee Jay M, Dohadwala Mariam, Gardner Brian K, Reckamp Karen L, Garon Edward, St John Maie, Sharma Sherven, Dubinett Steven M, Inflammation, epithelial to mesenchymal transition, and epidermal growth factor receptor tyrosine kinase inhibitor resistance, Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer, 2008, 3 (2), 107-10.
Rettig Matthew, Trinidad Kenny, Pezeshkpour G, Frost Patrick, Sharma Sherven, Moatamed Farhad, Tamanoi Fuyuhiko, Mortazavi Fariborz, PAK1 kinase promotes cell motility and invasiveness through CRK-II serine phosphorylation in non-small cell lung cancer cells, PloS one, 2012, 7 (7), e42012.
Hazra Saswati, Peebles Katherine A, Sharma Sherven, Mao Jenny T, Dubinett Steven M, The Role of PPARgamma in the Cyclooxygenase Pathway in Lung Cancer, PPAR research, 2008, 2008 (2), 790568.
Kar Upendra K, Jiang Janina, Champion Cheryl I, Salehi Sahar, Srivastava Minu, Sharma Sherven, Rabizadeh Shahrooz, Niazi Kayvan, Kickhoefer Valerie, Rome Leonard H, Kelly Kathleen A, Vault nanocapsules as adjuvants favor cell-mediated over antibody-mediated immune responses following immunization of mice, PloS one, 2012, 7 (7), e38553.
Liu Ming, Yang Seok-Chul, Sharma Sherven, Luo Jie, Cui Xiaoyan, Peebles Katherine A, Huang Min, Sato Mitsuo, Ramirez Ruben D, Shay Jerry W, Minna John D, Dubinett Steven M, EGFR signaling is required for TGF-beta 1 mediated COX-2 induction in human bronchial epithelial cells, American journal of respiratory cell and molecular biology, 2007, 37 (5), 578-88.
Peebles Katherine A, Lee Jay M, Mao Jenny T, Hazra Saswati, Reckamp Karen L, Krysan Kostyantyn, Dohadwala Mariam, Heinrich Eileen L, Walser Tonya C, Cui Xiaoyan, Baratelli Felicita E, Garon Edward, Sharma Sherven, Dubinett Steven M, Inflammation and lung carcinogenesis: applying findings in prevention and treatment, Expert review of anticancer therapy, 2007, 7 (10), 1405-21.
Hazra Saswati, Batra Raj K, Tai Hsin H, Sharma Sherven, Cui Xiaoyan, Dubinett Steven M, Pioglitazone and rosiglitazone decrease prostaglandin E2 in non-small-cell lung cancer cells by up-regulating 15-hydroxyprostaglandin dehydrogenase, Molecular pharmacology, 2007, 71 (6), 1715-20.
Hoang Bao, Zhu Li, Shi Yijiang, Frost Patrick, Yan Huajun, Sharma Sanjai, Sharma Sherven, Goodglick Lee, Dubinett Steven, Lichtenstein Alan, Oncogenic RAS mutations in myeloma cells selectively induce cox-2 expression, which participates in enhanced adhesion to fibronectin and chemoresistance, Blood, 2006, 107 (11), 4484-90.
Cui Xiaoyan, Yang Seok-Chul, Sharma Sherven, Heuze-Vourc'h Nathalie, Dubinett Steven M, IL-4 regulates COX-2 and PGE2 production in human non-small cell lung cancer, Biochemical and biophysical research communications, 2006, 343 (4), 995-1001.
Krysan Kostyantyn, Reckamp Karen L, Sharma Sherven, Dubinett Steven M, The potential and rationale for COX-2 inhibitors in lung cancer, Anti-cancer agents in medicinal chemistry, 2006, 6 (3), 209-20.
Yang Seok-Chul, Batra Raj K, Hillinger Sven, Reckamp Karen L, Strieter Robert M, Dubinett Steven M, Sharma Sherven, Intrapulmonary administration of CCL21 gene-modified dendritic cells reduces tumor burden in spontaneous murine bronchoalveolar cell carcinoma, Cancer research, 2006, 66 (6), 3205-13.
Pan Judong, Burdick Marie D, Belperio John A, Xue Ying Ying, Gerard Craig, Sharma Sherven, Dubinett Steven M, Strieter Robert M, CXCR3/CXCR3 ligand biological axis impairs RENCA tumor growth by a mechanism of immunoangiostasis, Journal of immunology (Baltimore, Md. : 1950), 2006, 176 (3), 1456-64.